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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MUSK
All Species:
25.76
Human Site:
S293
Identified Species:
47.22
UniProt:
O15146
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15146
NP_005583.1
869
97056
S293
N
K
H
G
E
K
F
S
T
A
K
A
A
A
T
Chimpanzee
Pan troglodytes
Q5IS37
825
92786
S293
A
E
N
V
V
G
M
S
N
A
S
V
A
L
T
Rhesus Macaque
Macaca mulatta
XP_001106626
869
96940
S293
N
K
H
G
E
K
F
S
T
A
K
A
A
A
T
Dog
Lupus familis
XP_538784
992
109405
S293
N
K
H
G
E
K
F
S
T
A
K
A
A
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q61006
868
96674
S293
N
K
H
G
E
K
F
S
T
A
K
A
A
A
T
Rat
Rattus norvegicus
Q62838
868
96804
S293
N
K
H
G
E
K
F
S
T
A
K
A
A
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508938
874
97520
S302
N
K
H
G
E
K
L
S
T
A
K
A
A
A
T
Chicken
Gallus gallus
Q8AXY6
947
105570
G293
N
K
H
S
K
T
F
G
A
A
K
A
A
A
T
Frog
Xenopus laevis
Q9PVZ4
1362
153727
I425
F
F
R
K
L
R
L
I
R
G
E
V
L
E
A
Zebra Danio
Brachydanio rerio
NP_001004503
941
106241
N290
N
R
H
S
G
G
E
N
T
V
K
A
T
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6K3
724
81818
Y204
M
R
R
P
N
C
S
Y
I
G
L
T
E
L
K
Honey Bee
Apis mellifera
XP_391863
648
74770
D129
I
E
D
N
K
Q
R
D
I
Y
I
R
S
R
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Q26614
972
110463
T311
L
E
C
G
A
R
G
T
P
T
P
N
I
T
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.7
99.1
80.9
N.A.
93
93.4
N.A.
82.7
71.3
20.1
59
N.A.
29.9
33.5
N.A.
22.5
Protein Similarity:
100
42.9
99.5
82.5
N.A.
96.4
96.8
N.A.
90.2
80.9
35.5
70.7
N.A.
44.9
48.3
N.A.
40
P-Site Identity:
100
26.6
100
100
N.A.
100
100
N.A.
93.3
66.6
0
40
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
40
100
100
N.A.
100
100
N.A.
93.3
73.3
13.3
53.3
N.A.
6.6
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
0
0
8
62
0
62
62
62
8
% A
% Cys:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
24
0
0
47
0
8
0
0
0
8
0
8
8
0
% E
% Phe:
8
8
0
0
0
0
47
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
54
8
16
8
8
0
16
0
0
0
0
8
% G
% His:
0
0
62
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
8
16
0
8
0
8
0
0
% I
% Lys:
0
54
0
8
16
47
0
0
0
0
62
0
0
0
16
% K
% Leu:
8
0
0
0
8
0
16
0
0
0
8
0
8
16
0
% L
% Met:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
62
0
8
8
8
0
0
8
8
0
0
8
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
8
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
16
16
0
0
16
8
0
8
0
0
8
0
8
0
% R
% Ser:
0
0
0
16
0
0
8
54
0
0
8
0
8
0
0
% S
% Thr:
0
0
0
0
0
8
0
8
54
8
0
8
8
8
62
% T
% Val:
0
0
0
8
8
0
0
0
0
8
0
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _